Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 9/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347324 | 0.86 | DYRK1A (0.42) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3347271 | 0.86 | DYRK1A (0.42) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3347239 | 0.86 | DYRK1A (0.45) | DYRK1AGRM5TGFBR1SCN5APIK3CD | |
| SCHEMBL3346211 | 0.81 | DYRK1A (0.41) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3348904 | 0.81 | TGFBR1 (0.46) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3346476 | 0.79 | DYRK1A (0.41) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3346984 | 0.79 | DYRK1A (0.41) | DYRK1AGRM5TGFBR1SCN5APIK3CD | |
| SCHEMBL3346980 | 0.78 | GRM5 (0.49) | GRM5PDGFRBKDR | |
| SCHEMBL3346921 | 0.77 | KCNN3 (0.37) | GRM5 | |
| SCHEMBL3346724 | 0.77 | GRM5 (0.46) | DYRK1AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |