Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 5/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353295 | 0.88 | GPR88 (0.52) | GPR88KCNH2KCNQ3KCNQ2TDP1 | |
| SCHEMBL3412005 | 0.86 | KCNH2 (0.55) | GPR88KCNH2KCNQ3KCNQ2TDP1 | |
| SCHEMBL3353012 | 0.84 | KCNH2 (0.59) | GPR88KCNH2KCNA5KCNQ3KCNQ2 | |
| SCHEMBL3416539 | 0.82 | GPR88 (0.45) | GPR88KCNH2KCNQ3KCNQ2TDP1 | |
| SCHEMBL3353261 | 0.82 | GPR88 (0.46) | GPR88KCNQ3KCNQ2TDP1 | |
| SCHEMBL2496243 | 0.80 | GPR88 (1.00) | GPR88 | |
| SCHEMBL13364990 | 0.79 | KCNH2 (0.69) | KCNH2TDP1MC4R | |
| SCHEMBL22856675 | 0.78 | GPR88 (0.71) | GPR88KCNQ3KCNQ2 | |
| SCHEMBL15248899 | 0.78 | GPR88 (0.71) | GPR88KCNQ3KCNQ2 | |
| SCHEMBL15239361 | 0.78 | GPR88 (0.71) | GPR88KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |