Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353261 | 0.87 | GPR88 (0.46) | GPR88TDP1RENTAS1R3TAS1R1 | |
| SCHEMBL13365126 | 0.86 | KCNH2 (0.52) | SLC6A2KCNH2ROCK2KCNQ3KCNQ2 | |
| SCHEMBL3346531 | 0.82 | GPR88 (0.66) | GPR88TDP1KCNH2KCNQ3KCNQ2 | |
| SCHEMBL3353012 | 0.81 | KCNH2 (0.59) | GPR88TDP1KCNH2KCNQ3KCNQ2 | |
| SCHEMBL3353295 | 0.79 | GPR88 (0.52) | GPR88TDP1KCNH2KCNQ3KCNQ2 | |
| SCHEMBL2229909 | 0.78 | MC4R (0.63) | SLC6A2KCNH2ROCK2 | |
| SCHEMBL3353040 | 0.78 | KCNH2 (0.48) | SLC6A2KCNH2ROCK2KCNQ3KCNQ2 | |
| SCHEMBL3353232 | 0.76 | POLB (0.53) | SLC6A2KCNH2ROCK2 | |
| SCHEMBL3346605 | 0.76 | KCNH2 (0.55) | SLC6A2KCNH2ROCK2KCNQ3KCNQ2 | |
| SCHEMBL12188593 | 0.75 | SLC6A2 (0.46) | SLC6A2KCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |