SCHEMBL33466

SCHEMBL33466

C=CC(=O)NC(C)(C)C(=O)N1CC1C

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
MAPT P10636 1/20 0.32
F13A1 P00488 1/20 0.31
TGM2 P21980 1/20 0.31
TGM1 P22735 1/20 0.31
GAA P10253 1/20 0.31
PDK1 Q15118 1/20 0.30
PDK2 Q15119 1/20 0.30
PDK3 Q15120 1/20 0.30
PDK4 Q16654 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33461 0.77 MEN1 (0.43) MEN1KMT2ATSHRALDH1A1CYP3A4
SCHEMBL33464 0.74 TSHR (0.37) TSHRMAPTGAAPDK1PDK2
SCHEMBL3116054 0.71 ALDH1A1 (0.43) MEN1KMT2ATSHRALDH1A1CYP3A4
SCHEMBL379428 0.69 ALDH1A1 (0.42) MEN1KMT2ATSHRALDH1A1CYP3A4
SCHEMBL1420537 0.69 ALDH1A1 (0.46) MEN1KMT2ATSHRALDH1A1CYP3A4
SCHEMBL673556 0.68 TSHR (0.44) TSHRMAPTGAAPDK1PDK2
SCHEMBL27640713 0.67 ALDH1A1 (0.44) MEN1KMT2ATSHRALDH1A1CYP3A4
SCHEMBL1420931 0.67 ALDH1A1 (0.41) MEN1KMT2ATSHRALDH1A1CYP3A4
SCHEMBL2033628 0.66
SCHEMBL4314501 0.66 ALDH1A1 (0.43) MEN1KMT2ATSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10093753-B2 Syrup polymer compositions and adhesives therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-10-09 US disclosed
US-20170362348-A1 SYRUP POLYMER COMPOSITIONS AND ADHESIVES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2017-12-21 US disclosed
US-20170362348-A1 SYRUP POLYMER COMPOSITIONS AND ADHESIVES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2017-12-21 US disclosed
US-20170362348-A1 SYRUP POLYMER COMPOSITIONS AND ADHESIVES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2017-12-21 US disclosed
EP-3227347-A1 SYRUP POLYMER COMPOSITIONS AND ADHESIVES THEREFROM 3M Innovative Properties Company (US) 2017-10-11 EP disclosed
WO-2016089805-A1 SYRUP POLYMER COMPOSITIONS AND ADHESIVES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-09 WO disclosed
WO-2016089805-A1 SYRUP POLYMER COMPOSITIONS AND ADHESIVES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-09 WO disclosed
EP-2470616-B1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2013-05-29 EP disclosed
EP-2470616-B1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2013-05-29 EP disclosed
US-20130053508-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-02-28 US disclosed
US-8067504-B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-29 US disclosed
US-8067504-B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-29 US disclosed
US-20110077358-A1 Functional Polymer With Pendant Color Changing Indicator 3M INNOVATIVE PROPERTIES COMPANY 2011-03-31 US disclosed
US-20110077358-A1 Functional Polymer With Pendant Color Changing Indicator 3M INNOVATIVE PROPERTIES COMPANY 2011-03-31 US disclosed
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2011-03-03 US disclosed
WO-2011025651-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-03-03 WO disclosed
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2011-03-03 US disclosed
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2011-03-03 US disclosed
CN-101687943-A Functionalized polymeric with pendant color changing indicator 3M INNOVATIVE PROPERTIES CO 2010-03-31 CN disclosed
WO-2009006254-A1 A FUNCTIONAL POLYMER WITH A PENDANT COLOR CHANGING INDICATOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS AAAS, PTK2, MDN1 MEN1 981/4885KMT2A 265/4885TSHR 4840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.