Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | GPR39 | O43194 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346548 | 0.88 | GPBAR1 (0.39) | MC4RROCK2FPR3TRPM5 | |
| SCHEMBL3346450 | 0.83 | FPR3 (0.48) | MC4RMAPTROCK2FPR3 | |
| SCHEMBL3346695 | 0.82 | CNR1 (0.50) | MC4RMAPTROCK2 | |
| SCHEMBL3350848 | 0.80 | ROCK2 (0.41) | MC4RROCK2TRPM5 | |
| SCHEMBL3349714 | 0.80 | MC4R (0.57) | MC4RMAPT | |
| SCHEMBL3350808 | 0.79 | TAAR1 (0.53) | MC4RTP53 | |
| SCHEMBL3346268 | 0.78 | KCNH2 (0.55) | MC4RLIPGGPR39 | |
| SCHEMBL3346031 | 0.77 | KCNH2 (0.53) | MC4RTP53MAPTROCK2 | |
| SCHEMBL3350885 | 0.76 | TAAR1 (0.47) | MC4RMAPT | |
| SCHEMBL21036525 | 0.74 | PTK2 (0.36) | TRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |