Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL33470 | 1.00 | ALDH1A1 (0.74) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL14920338 | 0.97 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL28724935 | 0.95 | ALDH1A1 (0.67) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL9331101 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL11837131 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL11753136 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL11745843 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL11745850 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL7513570 | 0.89 | ALDH1A1 (0.93) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL14660120 | 0.88 | ALDH1A1 (0.64) | ALDH1A1ALOX15AKR1C3HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359368-A1 | COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE | WockLab GmbH & Co. KG (DE) | 2024-05-01 | — | — | EP | claimed |
| WO-2022268777-A1 | COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE | WOCKLAB GMBH & CO. KG (DE) | 2022-12-29 | — | — | WO | claimed |
| US-11539074-B2 | Artificial solid electrolyte interface (A-SEI) cap layer including graphene layers with flexible wrinkle areas | Lyten, Inc. (US) | 2022-12-27 | — | — | US | claimed |
| US-20210126287-A1 | ARTIFICIAL SOLID ELECTROLYTE INTERFACE (A-SEI) CAP LAYER INCLUDING GRAPHENE LAYERS WITH FLEXIBLE WRINKLE AREAS | Lyten, Inc. (US) | 2021-04-29 | — | — | US | claimed |
| US-20210126286-A1 | ARTIFICIAL SOLID ELECTROLYTE INTERFACE CAP LAYER FOR AN ANODE IN A LI S BATTERY SYSTEM | Lyten, Inc. (US) | 2021-04-29 | — | — | US | claimed |
| CN-1370522-A | Method of producing penetrating pump capsule as one new dosage form | UNIV SHENYANG PHARMACY (CN) | 2002-09-25 | — | — | CN | claimed |
| CN-114471697-B | Treatment method of titanium-containing molecular sieve | 中国石油化工股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| US-11735740-B2 | Protective carbon layer for lithium (Li) metal anodes | Lyten, Inc. (US) | 2023-08-22 | — | — | US | disclosed |
| CN-112876378-B | Polymers prepared from mevalonic lactones and derivatives | 维索利斯有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-11631893-B2 | Artificial solid electrolyte interface cap layer for an anode in a Li S battery system | Lyten, Inc. (US) | 2023-04-18 | — | — | US | disclosed |
| US-20230067032-A1 | PROTECTIVE CARBON LAYER FOR LITHIUM (LI) METAL ANODES | Lyten, Inc. (US) | 2023-03-02 | — | — | US | disclosed |
| US-11539074-B2 | Artificial solid electrolyte interface (A-SEI) cap layer including graphene layers with flexible wrinkle areas | Lyten, Inc. (US) | 2022-12-27 | — | — | US | disclosed |
| WO-2022056008-A1 | ARTIFICIAL SOLID ELECTROLYTE INTERFACE CAP LAYER FOR AN ANODE IN A LI S BATTERY SYSTEM | Lyten, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |
| CN-100358508-C | Delay, control release drug of prepared aconite root which can regulate the function of middle-warmer, and its preparation method | UNIV SHENYANG PHARMACEUTICAL (CN) | 2008-01-02 | — | — | CN | disclosed |
| US-6773564-B1 | REACTION LAYER CONTAINS PHTHALIC ACID OR A PHTHALATE, AND A GLUCOSE DEHYDROGENASE WHOSE COENZYME IS PYRROLO-QUINOLINE QUINONE; STABILIZER; BIOSENSOR | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2004-08-10 | — | — | US | disclosed |
| CN-1481854-A | Delay, control release drug of prepared aconite root which can regulate the function of middle-warmer, and its preparation method | 沈阳药科大学 | 2004-03-17 | — | — | CN | disclosed |
| CN-1370522-A | Method of producing penetrating pump capsule as one new dosage form | UNIV SHENYANG PHARMACY (CN) | 2002-09-25 | — | — | CN | disclosed |
| US-6248862-B1 | PRODUCED BY CULTIVATING A PHA-PRODUCING MICROORGANISM IN THE PRESENCE OF AN ALIPHATIC DIOL OR AN ALIPHATIC POLYOL. | MONSANTO COMPANY | 2001-06-19 | — | — | US | disclosed |
| EP-0165174-A2 | Stabilized unsaturated polyesters | NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NASA as represented by the Administrator of NASA (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4207224-A | Plastics composition | CIBA-GEIGY AG (CH) | 1980-06-10 | — | — | US | disclosed |