Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL33468 | 1.00 | ALDH1A1 (0.74) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL14920338 | 0.97 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL28724935 | 0.95 | ALDH1A1 (0.67) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL9331101 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL11837131 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL11753136 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL11745843 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL11745850 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL7513570 | 0.89 | ALDH1A1 (0.93) | ALDH1A1ALOX15AKR1C3HPGDKDM4E | |
| Phthalic Acid SCHEMBL14660120 | 0.88 | ALDH1A1 (0.64) | ALDH1A1ALOX15AKR1C3HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359368-A1 | COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE | WockLab GmbH & Co. KG (DE) | 2024-05-01 | — | — | EP | claimed |
| WO-2022268777-A1 | COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE | WOCKLAB GMBH & CO. KG (DE) | 2022-12-29 | — | — | WO | claimed |
| CN-114471697-B | Treatment method of titanium-containing molecular sieve | 中国石油化工股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-2931756-B1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2018-08-08 | — | — | EP | disclosed |
| US-9463146-B2 | Addition-fragmentation oligomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-10-11 | — | — | US | disclosed |
| US-20150328086-A1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-11-19 | — | — | US | disclosed |
| EP-2931756-A1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M Innovative Properties Company (US) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014099317-A1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-06-26 | — | — | WO | disclosed |
| EP-2470616-B1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2013-05-29 | — | — | EP | disclosed |
| US-20130053508-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-28 | — | — | US | disclosed |
| US-8349962-B2 | Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2470616-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS | 3M Innovative Properties Company (US) | 2012-07-04 | — | — | EP | disclosed |
| US-20120028043-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-02-02 | — | — | US | disclosed |
| US-8067504-B2 | Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110054115-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2011-03-03 | — | — | US | disclosed |
| WO-2011025651-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-03 | — | — | WO | disclosed |
| US-6773564-B1 | REACTION LAYER CONTAINS PHTHALIC ACID OR A PHTHALATE, AND A GLUCOSE DEHYDROGENASE WHOSE COENZYME IS PYRROLO-QUINOLINE QUINONE; STABILIZER; BIOSENSOR | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2004-08-10 | — | — | US | disclosed |
| US-6248862-B1 | PRODUCED BY CULTIVATING A PHA-PRODUCING MICROORGANISM IN THE PRESENCE OF AN ALIPHATIC DIOL OR AN ALIPHATIC POLYOL. | MONSANTO COMPANY | 2001-06-19 | — | — | US | disclosed |
| US-4207224-A | Plastics composition | CIBA-GEIGY AG (CH) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054115-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS | AAAS, PTK2, MDN1 | ALDH1A1 492/4885ALOX15 188/4885AKR1C3 3074/4885 |
| US-20150328086-A1 | ADDITION-FRAGMENTATION OLIGOMERS | FGB, ZYX, APBA1 | ALDH1A1 1881/4885ALOX15 1222/4885AKR1C3 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.