Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | CBLB | Q13191 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346995 | 0.84 | GRM5 (0.56) | MEN1TSHRKMT2AOGAALDH1A1 | |
| SCHEMBL3348360 | 0.80 | GRM5 (0.44) | MEN1TSHRKMT2AOGARET | |
| SCHEMBL3346817 | 0.77 | DYRK1A (0.41) | OGARAB9ALMNASMN1; SMN2CYP11B1 | |
| SCHEMBL3348379 | 0.77 | CYP11B1 (0.38) | MEN1TSHRKMT2AOGARAB9A | |
| SCHEMBL3345949 | 0.77 | GRM5 (0.42) | MEN1KMT2AALDH1A1KDM4EGRM5 | |
| SCHEMBL3345883 | 0.76 | DYRK1A (0.37) | OGAGRM5 | |
| SCHEMBL3346876 | 0.75 | CYP19A1 (0.42) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL3346985 | 0.70 | GRM5 (0.42) | OGAALDH1A1GRM5 | |
| SCHEMBL3348249 | 0.70 | KDR (0.64) | RAB9ALMNAKDM4EGRM5SMN1; SMN2 | |
| SCHEMBL11202832 | 0.69 | NPSR1 (0.55) | MEN1TSHRKMT2ARAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |