Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 7/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335811 | 0.70 | TAAR1 (0.43) | TAAR1 | |
| SCHEMBL5403210 | 0.69 | NR1H2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL12125009 | 0.69 | TAAR1 (0.43) | TAAR1KDRTRPV1 | |
| SCHEMBL14018422 | 0.65 | KDM4E (0.47) | NR1H2NR1H3 | |
| SCHEMBL28794563 | 0.65 | KDM4E (0.47) | NR1H2NR1H3 | |
| SCHEMBL160602 | 0.65 | BTK (0.47) | KDR | |
| SCHEMBL11701106 | 0.64 | NR1H2 (0.43) | NR1H2NR1H3 | |
| SCHEMBL13365089 | 0.64 | TRPV3 (0.50) | CTSA | |
| SCHEMBL8464946 | 0.63 | NR1I2 (0.52) | TAAR1KDR | |
| SCHEMBL9667393 | 0.63 | NR1I2 (0.46) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | disclosed |