Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915928 | 1.00 | ADRA2C (0.48) | ADRA2CCHRM5ADRA2AADRA2BADRA1D | |
| SCHEMBL19749861 | 1.00 | ADRA2C (0.48) | ADRA2CCHRM5ADRA2AADRA2BADRA1D | |
| SCHEMBL18638043 | 1.00 | ADRA2C (0.48) | ADRA2CCHRM5ADRA2AADRA2BADRA1D | |
| SCHEMBL18638041 | 1.00 | ADRA2C (0.48) | ADRA2CCHRM5ADRA2AADRA2BADRA1D | |
| SCHEMBL6577437 | 1.00 | ADRA2C (0.48) | ADRA2CCHRM5ADRA2AADRA2BADRA1D | |
| SCHEMBL3357474 | 1.00 | ADRA2C (0.48) | ADRA2CCHRM5ADRA2AADRA2BADRA1D | |
| SCHEMBL18769020 | 1.00 | ADRA2C (0.48) | ADRA2CCHRM5ADRA2AADRA2BADRA1D | |
| SCHEMBL335246 | 0.97 | — | — | |
| SCHEMBL16274766 | 0.90 | TP53 (0.42) | ADRA2CCHRM5ADRA2AADRA2BADRA1D | |
| SCHEMBL608892 | 0.87 | HRH3 (0.48) | ADRA2CCHRM5ADRA2AADRA2BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633755-B2 | Copper plating bath composition and method for deposition of copper | ATOTECH DEUTSCHLAND GMBH (DE) | 2020-04-28 | — | — | US | claimed |
| US-20180237932-A1 | COPPER PLATING BATH COMPOSITION AND METHOD FOR DEPOSITION OF COPPER | ATOTECH USA, LLC | 2018-08-23 | — | — | US | claimed |
| EP-3141633-B1 | COPPER PLATING BATH COMPOSITION | ATOTECH DEUTSCHLAND GMBH (DE) | 2018-05-02 | — | — | EP | claimed |
| EP-3141633-A1 | COPPER PLATING BATH COMPOSITION | ATOTECH Deutschland GmbH (DE) | 2017-03-15 | — | — | EP | claimed |
| US-4421566-A | FROM HIGH AMYLOSE STARCH | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1983-12-20 | — | — | US | claimed |
| JP-58067667-A | — | — | None | — | — | JP | disclosed |
| CN-118420883-A | Super-gradient crosslinking anion exchange membrane and preparation method and application thereof | 苏州大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-112538084-B | Novel KRAS G12C protein inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2023-06-20 | — | — | CN | disclosed |
| US-20220135544-A1 | PYRAZOLYL QUINOXALINE KINASE INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2022-05-05 | — | — | US | disclosed |
| US-20200131153-A1 | PYRAZOLYL QUINOXALINE KINASE INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2020-04-30 | — | — | US | disclosed |
| US-10633755-B2 | Copper plating bath composition and method for deposition of copper | ATOTECH DEUTSCHLAND GMBH (DE) | 2020-04-28 | — | — | US | disclosed |
| EP-3178818-B1 | PYRAZOLYL QUINOXALINE KINASE INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2019-05-22 | — | — | EP | disclosed |
| EP-0058434-B1 | N-2-HYDROXYPROPYL PIPERIDINES AND PROCESS FOR PREPARING THE SAME | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0029116-B1 | N(B)-QUATERNARY 10-BROMO-SANDWICINE AND 10-BROMO-ISOSANDWICINE DERIVATIVES, PROCESS AND INTERMEDIATES FOR PREPARING THE DERIVATIVES AND MEDICAMENTS CONTAINING THESE DERIVATIVES | Kali-Chemie Pharma GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |
| US-4421566-A | FROM HIGH AMYLOSE STARCH | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1983-12-20 | — | — | US | disclosed |
| US-4405737-A | OLEFIN STABILIZERS | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-09-20 | — | — | US | disclosed |
| JP-S5867667-A | 1-SUBSTITUTED-4-PHENYL-ISONICOPETINIC ACID ESTER | KAYAKU:KK | 1983-04-22 | — | — | JP | disclosed |
| EP-0058434-A1 | N-2-hydroxypropyl piperidines and process for preparing the same | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1982-08-25 | — | — | EP | disclosed |
| EP-0029116-A1 | N(b)-quaternary 10-bromo-sandwicine and 10-bromo-isosandwicine derivatives, process and intermediates for preparing the derivatives and medicaments containing these derivatives | Kali-Chemie Pharma GmbH (DE) | 1981-05-27 | — | — | EP | disclosed |
| US-4241060-A | FOR SENSITIZING HYPOXIC CELLS TO RADIATION; ANTIPROTOZAL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131153-A1 | PYRAZOLYL QUINOXALINE KINASE INHIBITORS | PDXK, DCK, PDPK1 | ADRA2C 2726/4885CHRM5 3827/4885ADRA2A 3350/4885 |
| US-20220135544-A1 | PYRAZOLYL QUINOXALINE KINASE INHIBITORS | PDXK, DCK, PDPK1 | ADRA2C 2726/4885CHRM5 3827/4885ADRA2A 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.