Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345981 | 0.85 | GRM5 (0.52) | GRM5 | |
| SCHEMBL3348468 | 0.84 | GRM5 (0.45) | GRM5TGFBR1 | |
| SCHEMBL3347060 | 0.84 | GRM5 (0.35) | GRM5TGFBR1 | |
| SCHEMBL3347007 | 0.81 | GRM5 (0.43) | GRM5 | |
| SCHEMBL3346788 | 0.81 | GRM5 (0.32) | GRM5TGFBR1 | |
| SCHEMBL3347005 | 0.80 | ALOX5 (0.40) | GRM5TGFBR1 | |
| SCHEMBL3346516 | 0.80 | ALOX5 (0.37) | GRM5TGFBR1 | |
| SCHEMBL3346766 | 0.79 | GRM5 (0.53) | GRM5TGFBR1 | |
| SCHEMBL3347130 | 0.79 | CA12 (0.38) | — | |
| SCHEMBL3345876 | 0.77 | GRM5 (0.53) | GRM5TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |