Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354484 | 0.83 | ALDH1A1 (0.41) | WDR5ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL3354619 | 0.79 | ASH1L (0.39) | SLC6A4ALDH1A1HTT | |
| SCHEMBL3354615 | 0.79 | ASH1L (0.39) | SLC6A4ALDH1A1HTT | |
| SCHEMBL3353152 | 0.77 | IRAK4 (0.44) | IRAK4SLC6A4ALDH1A1MAPTMEN1 | |
| SCHEMBL3352705 | 0.77 | IRAK4 (0.44) | IRAK4SLC6A4ALDH1A1MAPTMEN1 | |
| SCHEMBL10863485 | 0.69 | PIK3CD (0.58) | ALDH1A1SMN1; SMN2LMNAKDM4EHTT | |
| SCHEMBL3357241 | 0.69 | ACHE (0.41) | WDR5ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL12996890 | 0.68 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL28596296 | 0.68 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL3355435 | 0.67 | ALDH1A1 (0.42) | SLC6A4ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |