Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353152 | 1.00 | IRAK4 (0.44) | IRAK4HTR7SLC6A4CDC7ALDH1A1 | |
| SCHEMBL3357611 | 0.83 | CDC7 (0.43) | HTR7CDC7ALDH1A1MAPTCYP1A2 | |
| SCHEMBL3353526 | 0.83 | CDC7 (0.43) | HTR7CDC7ALDH1A1MAPTCYP1A2 | |
| SCHEMBL3352455 | 0.82 | HTR7 (0.45) | HTR7CDC7MAPTCYP1A2 | |
| SCHEMBL3353280 | 0.82 | HTR7 (0.53) | HTR7SLC6A4CDC7MAPTHRH3 | |
| SCHEMBL3352450 | 0.82 | HTR7 (0.45) | HTR7CDC7MAPTCYP1A2 | |
| SCHEMBL3359093 | 0.81 | ALDH1A1 (0.41) | HTR7CDC7ALDH1A1MAPTSIRT2 | |
| SCHEMBL3353782 | 0.81 | ALDH1A1 (0.42) | HTR7SLC6A4CDC7ALDH1A1CYP1A2 | |
| SCHEMBL3357415 | 0.79 | HTR7 (0.42) | HTR7SLC6A4CDC7ALDH1A1MAPT | |
| SCHEMBL3358021 | 0.79 | HTR7 (0.47) | HTR7SLC6A4CDC7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |