Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355907 | 0.90 | ACHE (0.39) | ALDH1A1ACHEMAPTPKMAPP | |
| SCHEMBL3354484 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL3357241 | 0.83 | ACHE (0.41) | ALDH1A1KMT2ALMNAACHEMAPT | |
| SCHEMBL3354325 | 0.81 | AVPR1A (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL3354823 | 0.81 | LMNA (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL3358236 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL13537602 | 0.79 | OPRM1 (0.38) | ALDH1A1ERN1 | |
| SCHEMBL3352685 | 0.78 | MAPT (0.47) | ALDH1A1LMNAACHEMAPTAPP | |
| SCHEMBL3357600 | 0.78 | ACHE (0.42) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL13537477 | 0.78 | HTR1B (0.39) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |