Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196805 | 0.87 | KLK5 (0.53) | ALDH1A1TSHRP2RX7MEN1KMT2A | |
| SCHEMBL8685847 | 0.87 | KLK5 (0.53) | ALDH1A1TSHRP2RX7MEN1KMT2A | |
| SCHEMBL14189470 | 0.87 | KLK5 (0.53) | ALDH1A1TSHRP2RX7MEN1KMT2A | |
| SCHEMBL14209406 | 0.83 | KLK5 (0.46) | ALDH1A1TSHRP2RX7MEN1KMT2A | |
| SCHEMBL10209786 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRMMP13P2RX7MAPT | |
| SCHEMBL38652038 | 0.81 | MMP13 (0.50) | ALDH1A1TSHRMMP13P2RX7BCL2 | |
| SCHEMBL10569435 | 0.80 | CA2 (0.54) | ALDH1A1TSHRMMP13P2RX7MAPT | |
| SCHEMBL3375456 | 0.79 | KLK5 (0.47) | MMP13KLK5ATM | |
| SCHEMBL527832 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRMMP13P2RX7MAPT | |
| SCHEMBL527833 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRMMP13P2RX7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |