Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344715 | 0.89 | PTGDR2 (0.44) | CYP2C9ALDH1A1PTGDR2MAPTRORC | |
| SCHEMBL3348700 | 0.89 | ALDH1A1 (0.41) | CNR1CYP2C9HPGDALDH1A1POLB | |
| SCHEMBL3346117 | 0.84 | DDB1 (0.41) | CNR1ACLYCYP2C9HPGDALDH1A1 | |
| SCHEMBL3345079 | 0.80 | ALDH1A1 (0.42) | HPGDALDH1A1KDM4EHSD17B10PTGDR2 | |
| SCHEMBL3345068 | 0.79 | CYP2C9 (0.41) | CYP2C9ALDH1A1KDM4EMAPTCYP2C19 | |
| SCHEMBL3344676 | 0.77 | TDP1 (0.44) | HPGDALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL3348099 | 0.72 | HPGD (0.41) | CNR1CYP2C9HPGDALDH1A1POLB | |
| SCHEMBL2570439 | 0.72 | ALDH1A1 (0.35) | CNR1CYP2C9HPGDALDH1A1POLB | |
| SCHEMBL2576023 | 0.72 | HPGD (0.35) | ACLYCYP2C9HPGDALDH1A1POLB | |
| SCHEMBL3345539 | 0.71 | ALDH1A1 (0.46) | HPGDALDH1A1KDM4EHSD17B10PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |