Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345917 | 0.83 | GRM5 (0.44) | TGFBR1DYRK1AOGASCN5AGRM5 | |
| SCHEMBL3347027 | 0.78 | GRM5 (0.50) | TGFBR1DYRK1AGRM5 | |
| SCHEMBL3346833 | 0.77 | GRM5 (0.50) | TGFBR1DYRK1AOGASCN5AGRM5 | |
| SCHEMBL3346192 | 0.77 | GRM5 (0.47) | TGFBR1DYRK1AOGASCN5AGRM5 | |
| SCHEMBL3347208 | 0.77 | DYRK1A (0.36) | TGFBR1DYRK1AOGASCN5AGRM5 | |
| SCHEMBL3346819 | 0.77 | SCN5A (0.39) | TGFBR1DYRK1AOGASCN5AGRM5 | |
| SCHEMBL3346922 | 0.76 | GRM5 (0.39) | TGFBR1DYRK1AGRM5 | |
| SCHEMBL3346568 | 0.76 | GRM5 (0.43) | TGFBR1DYRK1AOGASCN5AGRM5 | |
| SCHEMBL3346603 | 0.75 | GRM5 (0.41) | TGFBR1DYRK1AOGASCN5AGRM5 | |
| SCHEMBL3347519 | 0.73 | GRM4 (0.46) | DYRK1AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |