Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | DDO | Q99489 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344690 | 0.84 | SMN1; SMN2 (0.49) | ALDH1A1KDM4ECYP1A2DAO | |
| SCHEMBL3346540 | 0.80 | ALDH1A1 (0.47) | ALDH1A1IDH1NQO1MEN1KMT2A | |
| SCHEMBL3349059 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EDAO | |
| SCHEMBL3349053 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPK1KDM4E | |
| SCHEMBL3350433 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AKDM4EDAO | |
| SCHEMBL3345086 | 0.72 | ALKBH3 (0.42) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL6584194 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL15931670 | 0.71 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4EDAO | |
| SCHEMBL6583759 | 0.70 | KDM4E (0.67) | ALDH1A1NQO1MEN1KMT2AGLA | |
| SCHEMBL14246752 | 0.69 | DAO (0.45) | ALDH1A1MEN1KMT2AKDM4EDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |