Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | GPR39 | O43194 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 2/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14909228 | 0.81 | PRKCQ (0.41) | MAP4K4HTR6PIM1PIM2UTS2R | |
| SCHEMBL28165149 | 0.75 | TRPV1 (0.43) | MAP4K4HTR6UTS2RKDM4CKHK | |
| SCHEMBL30996050 | 0.70 | GRM4 (0.54) | MAP4K4CD38UTS2RGPR39KDM4C | |
| SCHEMBL14022904 | 0.69 | ALDH1A1 (0.42) | HTR6PIM1PIM3PIM2KDM4C | |
| SCHEMBL18205898 | 0.69 | CA12 (0.53) | HTR6UTS2RNSD2 | |
| SCHEMBL3908444 | 0.69 | HTR6 (0.46) | HTR6PIM1PIM3PIM2SLC40A1 | |
| SCHEMBL3914009 | 0.67 | KCNH3 (0.40) | HTR6PIM1PIM3PIM2 | |
| SCHEMBL3918087 | 0.67 | PIM1 (0.40) | HTR6PIM1PIM2SLC40A1 | |
| SCHEMBL18205924 | 0.66 | UTS2R (0.48) | CD38HTR6UTS2RNSD2KHK | |
| SCHEMBL3511163 | 0.63 | CRHR1 (0.52) | UTS2RGPR39KDM4CKHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002577-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | 富士フイルム株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |