Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350657 | 0.75 | DHODH (0.41) | DHODHEZH2MCL1 | |
| SCHEMBL3430623 | 0.70 | FFAR1 (0.43) | DHODHFFAR4FFAR1PTGER4KDM4E | |
| SCHEMBL3346086 | 0.69 | PTGER4 (0.44) | DHODHGRIN1GRIN2BGPR17PTGER4 | |
| SCHEMBL3352922 | 0.69 | GSK3B (0.38) | DHODHFFAR4FFAR1PTGER4 | |
| SCHEMBL31424869 | 0.67 | RHEB (0.42) | DHODHGRIN1GRIN2B | |
| SCHEMBL9372308 | 0.66 | PDE3B (0.55) | — | |
| SCHEMBL31424666 | 0.65 | SLC6A4 (0.38) | DHODHGRIN1GRIN2B | |
| SCHEMBL9371196 | 0.65 | PDE3B (0.56) | — | |
| SCHEMBL31424682 | 0.65 | GRIN1 (0.37) | DHODHGRIN1GRIN2B | |
| SCHEMBL31424693 | 0.65 | GRIN1 (0.37) | DHODHGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |