Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352922 | 0.83 | GSK3B (0.38) | FFAR1FFAR4IDH1DHODHCYP2C9 | |
| SCHEMBL3430044 | 0.77 | FFAR1 (0.48) | FFAR1FFAR4DHODH | |
| SCHEMBL3349649 | 0.76 | FFAR1 (0.45) | FFAR1FFAR4HPGDHTTDHODH | |
| SCHEMBL3431395 | 0.73 | HTT (0.56) | KDM4EALDH1A1GAAHPGDHTT | |
| SCHEMBL3428421 | 0.73 | PPARD (0.39) | PPARD | |
| SCHEMBL3431483 | 0.71 | FFAR1 (0.43) | FFAR1FFAR4DHODHPPARD | |
| SCHEMBL2534776 | 0.70 | FFAR1 (0.56) | FFAR1FFAR4PLA2G4APTGER4PTGER3 | |
| SCHEMBL3346086 | 0.70 | PTGER4 (0.44) | KDM4EDHODHCYP2C9PTGER4PTGER3 | |
| SCHEMBL3350676 | 0.70 | DHODH (0.43) | FFAR1FFAR4KDM4EDHODHPTGER4 | |
| SCHEMBL3859024 | 0.70 | FFAR4 (0.51) | FFAR1FFAR4PLA2G4ACYP2C9CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |