Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 6/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347691 | 0.87 | FFAR4 (0.40) | DHODHGRIN1GRIN2BRXRARXRB | |
| SCHEMBL3346056 | 0.83 | S1PR1 (0.41) | GPR17RXRARXRBRXRG | |
| SCHEMBL3346903 | 0.82 | GRIN2B (0.36) | PARP1GRIN1GRIN2B | |
| SCHEMBL3431483 | 0.81 | FFAR1 (0.43) | DHODH | |
| SCHEMBL3430749 | 0.80 | GAA (0.43) | DHODHKDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3353013 | 0.77 | DHODH (0.45) | DHODHGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3430892 | 0.76 | FFAR4 (0.44) | CYP2C9 | |
| SCHEMBL3430044 | 0.75 | FFAR1 (0.48) | DHODHPARP1PARP2 | |
| SCHEMBL3346362 | 0.72 | DHODH (0.39) | DHODHKDM4EGRIN1GRIN2B | |
| SCHEMBL3431568 | 0.72 | RXRA (0.44) | PARP1GRIN1GRIN2BRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |