Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351499 | 0.89 | CNR1 (0.37) | PTGDR2RORCTSHRCYP2C9MEN1 | |
| SCHEMBL3344676 | 0.87 | TDP1 (0.44) | PPARDPPARGTSHRTDP1MEN1 | |
| SCHEMBL3345068 | 0.82 | CYP2C9 (0.41) | CYP2C9MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3345079 | 0.79 | ALDH1A1 (0.42) | PTGDR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3348700 | 0.77 | ALDH1A1 (0.41) | TSHRCYP2C9MEN1ALDH1A1MAPT | |
| SCHEMBL3404915 | 0.74 | PTGS1 (0.38) | CYP2C9MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3344758 | 0.72 | PTGDR2 (0.51) | PTGDR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3346117 | 0.72 | DDB1 (0.41) | TSHRTDP1CYP2C9MEN1ALDH1A1 | |
| SCHEMBL14317881 | 0.71 | MAPT (0.47) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3345539 | 0.70 | ALDH1A1 (0.46) | PTGDR2TSHRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |