Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30271240 | 0.90 | CHEK1 (0.42) | SCDKDM5ANR3C1ALOX15GPR119 | |
| SCHEMBL3353482 | 0.90 | CHEK1 (0.42) | SCDKDM5ANR3C1ALOX15GPR119 | |
| SCHEMBL3349663 | 0.85 | HTR1B (0.54) | HTR1AHTR1BHTR1FSCDPIK3CD | |
| SCHEMBL3369338 | 0.84 | PIK3CD (0.43) | HTR1AHTR1BHTR1FSCDPIK3CD | |
| SCHEMBL30778591 | 0.82 | KDM4E (0.43) | HTR1AHTR1BHTR1FSCDPIK3CD | |
| SCHEMBL3351511 | 0.82 | HTR1A (0.41) | HTR1AHTR1BHTR1FSCDPIK3CD | |
| SCHEMBL3351612 | 0.80 | OGFRL1 (0.40) | HTR1AHTR1BHTR1FSCDPIK3CD | |
| SCHEMBL3354280 | 0.80 | DRD2 (0.42) | HTR1AHTR1BHTR1FSCDALOX15 | |
| SCHEMBL3357810 | 0.79 | ALDH1A1 (0.40) | HTR1AHTR1BHTR1FSCDKDM5A | |
| SCHEMBL31482830 | 0.78 | PDE9A (0.39) | HTR1AHTR1BHTR1FSCDPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |