SCHEMBL33524077

SCHEMBL33524077

S=c1[nH]c2cc(Br)ccc2s1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 10/20 0.61
ALDH1A1 P00352 4/20 0.61
KDM4E B2RXH2 3/20 0.61
HPGD P15428 2/20 0.61
GAA P10253 2/20 0.61
CYP1A2 P05177 2/20 0.61
CYP2C19 P33261 2/20 0.61
CYP2C9 P11712 1/20 0.61
CYP3A4 P08684 1/20 0.59
ALOX15 P16050 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
GFER P55789 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24805460 0.76 PSMB8 (0.61) PSMB8ALDH1A1KDM4EHPGDGAA
SCHEMBL18791144 0.76 PSMB8 (0.61) PSMB8ALDH1A1KDM4EHPGDGAA
SCHEMBL9497675 0.76 PSMB8 (1.00) PSMB8ALDH1A1KDM4EHPGDGAA
SCHEMBL14403267 0.76 PSMB8 (0.61) PSMB8ALDH1A1KDM4EHPGDGAA
SCHEMBL11110131 0.76 PSMB8 (0.61) PSMB8ALDH1A1KDM4EHPGDGAA
SCHEMBL29477415 0.76 CMA1 (0.61) PSMB8ALDH1A1KDM4EHPGDGAA
SCHEMBL289800 0.76 CMA1 (0.61) PSMB8ALDH1A1KDM4EHPGDGAA
2-Mercaptobenzothiazole SCHEMBL408087 0.74 PSMB8 (1.00) PSMB8ALDH1A1KDM4EHPGDGAA
2-Mercaptobenzothiazole SCHEMBL29433968 0.74 PSMB8 (1.00) PSMB8ALDH1A1KDM4EHPGDGAA
2-Mercaptobenzothiazole SCHEMBL4268289 0.72 PSMB8 (0.95) PSMB8ALDH1A1KDM4EHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096279-A1 DISPLAY LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT EACH INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260096279-A1 DISPLAY LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT EACH INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND GPS1, GAR1, EMC1 PSMB8 3386/4885ALDH1A1 128/4885KDM4E 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.