Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352455 | 1.00 | HTR7 (0.45) | HTR7POLBCDC7NOS3NOS1 | |
| SCHEMBL3353280 | 0.84 | HTR7 (0.53) | HTR7CDC7NOS3NOS1NOS2 | |
| SCHEMBL3357611 | 0.83 | CDC7 (0.43) | HTR7POLBCDC7MAPTCYP1A2 | |
| SCHEMBL3353526 | 0.83 | CDC7 (0.43) | HTR7POLBCDC7MAPTCYP1A2 | |
| SCHEMBL3353152 | 0.82 | IRAK4 (0.44) | HTR7CDC7MAPTCYP1A2 | |
| SCHEMBL3352705 | 0.82 | IRAK4 (0.44) | HTR7CDC7MAPTCYP1A2 | |
| SCHEMBL3357415 | 0.81 | HTR7 (0.42) | HTR7POLBCDC7MAPTCYP1A2 | |
| SCHEMBL3354666 | 0.81 | HTR7 (0.46) | HTR7CDC7MAPTCYP1A2 | |
| SCHEMBL12253684 | 0.80 | HTR7 (0.55) | HTR7POLBNOS3NOS1NOS2 | |
| SCHEMBL3355938 | 0.80 | HTR7 (0.52) | HTR7POLBCDC7NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |