Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357611 | 1.00 | CDC7 (0.43) | CDC7HTR7CYP1A2SIRT2MAPT | |
| SCHEMBL3353782 | 0.84 | ALDH1A1 (0.42) | CDC7HTR7CYP1A2SIRT2ALDH1A1 | |
| SCHEMBL3359093 | 0.84 | ALDH1A1 (0.41) | CDC7HTR7SIRT2MAPTALDH1A1 | |
| SCHEMBL3352705 | 0.83 | IRAK4 (0.44) | CDC7HTR7CYP1A2SIRT2MAPT | |
| SCHEMBL3353152 | 0.83 | IRAK4 (0.44) | CDC7HTR7CYP1A2SIRT2MAPT | |
| SCHEMBL3352450 | 0.83 | HTR7 (0.45) | CDC7HTR7CYP1A2MAPTPOLB | |
| SCHEMBL3353280 | 0.83 | HTR7 (0.53) | CDC7HTR7MAPTHTR1AHTR1D | |
| SCHEMBL3352455 | 0.83 | HTR7 (0.45) | CDC7HTR7CYP1A2MAPTPOLB | |
| SCHEMBL3357757 | 0.81 | NPC1 (0.47) | CDC7HTR7CYP1A2SIRT2MAPT | |
| SCHEMBL3352991 | 0.80 | CDC7 (0.43) | CDC7HTR7SIRT2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |