Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537503 | 0.90 | MEN1 (0.42) | HTR7ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL3353280 | 0.86 | HTR7 (0.53) | HTR7CDC7HTR1AHTR1DHTR1B | |
| SCHEMBL3358021 | 0.83 | HTR7 (0.47) | HTR7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12253684 | 0.82 | HTR7 (0.55) | HTR7ALDH1A1HTR1AHTR1DHTR1B | |
| SCHEMBL3357757 | 0.81 | NPC1 (0.47) | HTR7ALDH1A1MEN1KMT2AOPRM1 | |
| SCHEMBL3352455 | 0.81 | HTR7 (0.45) | HTR7CDC7MAPTPOLBCYP1A2 | |
| SCHEMBL3352450 | 0.81 | HTR7 (0.45) | HTR7CDC7MAPTPOLBCYP1A2 | |
| SCHEMBL3354104 | 0.81 | DRD2 (0.60) | HTR7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3353782 | 0.80 | ALDH1A1 (0.42) | HTR7ALDH1A1CDC7SLC6A4CHRNB4 | |
| SCHEMBL3359093 | 0.80 | ALDH1A1 (0.41) | HTR7ALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |