Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | MELK | Q14680 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357845 | 0.87 | OPRM1 (0.49) | AVPR1AASH1LOPRM1OPRD1OPRK1 | |
| SCHEMBL3354345 | 0.87 | AVPR1A (0.46) | AVPR1AASH1LOPRM1OPRD1OPRK1 | |
| SCHEMBL13537313 | 0.84 | AVPR1A (0.41) | AVPR1AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3357600 | 0.82 | ACHE (0.42) | AVPR1AALDH1A1HTR6MEN1KMT2A | |
| SCHEMBL3356791 | 0.77 | ASH1L (0.39) | AVPR1AASH1LOPRM1OPRK1OPRL1 | |
| SCHEMBL3352326 | 0.76 | ASH1L (0.40) | AVPR1AASH1LHTR6HTR1DHTR1B | |
| SCHEMBL3356885 | 0.76 | KDM4E (0.42) | AVPR1AASH1LKDM4EALDH1A1HTR6 | |
| SCHEMBL3350475 | 0.73 | KDM1A (0.40) | ASH1L | |
| SCHEMBL13537308 | 0.72 | OPRM1 (0.47) | AVPR1AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13537280 | 0.71 | AVPR1A (0.44) | AVPR1AOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |