Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 15/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610394 | 0.87 | XDH (0.48) | KDM1AXDHASH1L | |
| SCHEMBL2877901 | 0.87 | XDH (0.46) | KDM1AXDHASH1L | |
| SCHEMBL3352326 | 0.80 | ASH1L (0.40) | KDM1AASH1L | |
| SCHEMBL3356885 | 0.80 | KDM4E (0.42) | ASH1L | |
| SCHEMBL3354823 | 0.80 | LMNA (0.43) | — | |
| SCHEMBL3356791 | 0.78 | ASH1L (0.39) | ASH1L | |
| SCHEMBL3357845 | 0.76 | OPRM1 (0.49) | ASH1L | |
| SCHEMBL3354345 | 0.76 | AVPR1A (0.46) | ASH1L | |
| SCHEMBL28587433 | 0.76 | XDH (0.54) | KDM1AXDH | |
| SCHEMBL2850331 | 0.74 | IMPDH2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |