Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.36 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357845 | 0.90 | OPRM1 (0.49) | AVPR1AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3352488 | 0.87 | AVPR1A (0.42) | AVPR1AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13537280 | 0.83 | AVPR1A (0.44) | AVPR1AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3354325 | 0.81 | AVPR1A (0.43) | AVPR1APTGDR2ALDH1A1MEN1KMT2A | |
| SCHEMBL3356791 | 0.80 | ASH1L (0.39) | AVPR1AOPRM1OPRK1OPRL1ASH1L | |
| SCHEMBL3352326 | 0.79 | ASH1L (0.40) | AVPR1AASH1LHTR1DHTR1BPRKCG | |
| SCHEMBL3356885 | 0.79 | KDM4E (0.42) | AVPR1AASH1LPTGDR2HTR1DHTR1B | |
| SCHEMBL3350475 | 0.76 | KDM1A (0.40) | ASH1L | |
| SCHEMBL13537308 | 0.75 | OPRM1 (0.47) | AVPR1AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3358236 | 0.73 | ALDH1A1 (0.47) | AVPR1AOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |