Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.36 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352326 | 0.83 | ASH1L (0.40) | ASH1LHTR1DHTR1BAVPR1APRKCG | |
| SCHEMBL3356791 | 0.81 | ASH1L (0.39) | ASH1LHTR1DHTR1BAVPR1APRKCG | |
| SCHEMBL3354619 | 0.81 | ASH1L (0.39) | ASH1LALDH1A1HTTPTGDR2PDE4A | |
| SCHEMBL3354615 | 0.81 | ASH1L (0.39) | ASH1LALDH1A1HTTPTGDR2PDE4A | |
| SCHEMBL3350475 | 0.80 | KDM1A (0.40) | ASH1L | |
| SCHEMBL13537284 | 0.80 | AVPR1A (0.38) | AVPR1APRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3354345 | 0.79 | AVPR1A (0.46) | KDM4EASH1LHTR1DHTR1BALDH1A1 | |
| SCHEMBL3357845 | 0.79 | OPRM1 (0.49) | KDM4EMAPTASH1LHTR1DHTR1B | |
| SCHEMBL3352488 | 0.76 | AVPR1A (0.42) | KDM4EASH1LHTR1DHTR1BALDH1A1 | |
| SCHEMBL15129299 | 0.76 | ALDH1A1 (0.37) | KDM4EMAPTRAD52ASH1LALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |