SCHEMBL33525267

SCHEMBL33525267

CC(C)(C)c1ccc2oc(Nc3ccc(N)cc3)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IL6 P05231 1/20 0.61
STAT3 P40763 1/20 0.61
MEN1 O00255 2/20 0.60
MAPT P10636 2/20 0.60
KMT2A Q03164 2/20 0.60
CSNK1D P48730 1/20 0.54
CSNK1G2 P78368 1/20 0.54
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
GFER P55789 1/20 0.51
FBP1 P09467 1/20 0.47
HDAC6 Q9UBN7 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18233032 0.86 NPC1 (0.60) IL6STAT3MEN1MAPTKMT2A
SCHEMBL33525283 0.82 IL6 (0.65) IL6STAT3MEN1MAPTKMT2A
SCHEMBL25291148 0.79 NPC1 (0.47) IL6STAT3MEN1MAPTKMT2A
SCHEMBL31532255 0.79 IL6 (0.61) IL6STAT3MEN1MAPTKMT2A
SCHEMBL25248374 0.79 IL6 (0.61) IL6STAT3MEN1MAPTKMT2A
SCHEMBL33525300 0.78 IL6 (0.61) IL6STAT3MEN1MAPTKMT2A
SCHEMBL30831274 0.78 MEN1 (0.53) IL6STAT3MEN1MAPTKMT2A
SCHEMBL15472493 0.77 NPC1 (0.69) MEN1MAPTKMT2ACSNK1DCSNK1G2
SCHEMBL2242200 0.76 RAB9A (0.84) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL12069188 0.76 IL6 (1.00) IL6STAT3MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092043-A1 NOVEL BENZOXAZOLE DERIVATIVE COMPRISING 4-AMINO-BUTANAMIDE AND USE THEREOF EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092043-A1 NOVEL BENZOXAZOLE DERIVATIVE COMPRISING 4-AMINO-BUTANAMIDE AND USE THEREOF IL4I1, GABRB1, IL1B IL6 6/4885STAT3 355/4885MEN1 4169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.