SCHEMBL33526600

SCHEMBL33526600

CNC(=O)Cn1nc(C(F)(F)F)cc1CO

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.50
▸ TP53 P04637 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ POLB P06746 3/20 0.46
▸ TSHR P16473 1/20 0.46
▸ CYP1A2 P05177 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ CYP2D6 P10635 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ GAA P10253 2/20 0.43
▸ ALDH1A1 P00352 4/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13184397 0.77 MPO (0.43) LMNATP53L3MBTL1POLBTSHR
SCHEMBL18695216 0.73 TP53 (0.42) LMNATP53L3MBTL1POLBTSHR
SCHEMBL2586705 0.72 LMNA (0.47) LMNATP53L3MBTL1POLBTSHR
SCHEMBL13169933 0.72 LMNA (0.47) LMNATP53L3MBTL1POLBTSHR
SCHEMBL18695215 0.71 L3MBTL1 (0.46) LMNATP53L3MBTL1CYP1A2CYP2D6
SCHEMBL19524908 0.71 LMNA (0.43) LMNATP53L3MBTL1POLBTSHR
SCHEMBL12198285 0.70 KMT2A (0.39) LMNAPOLBCYP3A4ALDH1A1KMT2A
SCHEMBL15133609 0.69 MAPK14 (0.50) LMNAGAAALDH1A1KDM4ENPSR1
SCHEMBL14487283 0.69 TP53 (0.47) LMNATP53L3MBTL1POLBTSHR
SCHEMBL18695214 0.69 TP53 (0.44) LMNATP53L3MBTL1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 LMNA 2816/4885TP53 4863/4885L3MBTL1 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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