Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537500 | 0.91 | PRKCG (0.48) | MAPTALDH1A1LMNAPRKCGPRKCB | |
| SCHEMBL15409864 | 0.86 | LMNA (0.47) | MAPTALDH1A1LMNAPRKCGPRKCB | |
| SCHEMBL3358142 | 0.82 | MAPT (0.52) | MAPTALDH1A1LMNAPRKCGPRKCB | |
| SCHEMBL1864820 | 0.82 | HCAR1 (0.52) | MAPTALDH1A1LMNAGPR119CYP1A2 | |
| SCHEMBL4898784 | 0.81 | SFRP1 (0.51) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL3354815 | 0.80 | MAPT (0.52) | MAPTALDH1A1LMNAPRKCGPRKCB | |
| SCHEMBL3352685 | 0.80 | MAPT (0.47) | MAPTALDH1A1LMNAPTGDR2 | |
| SCHEMBL1871066 | 0.79 | HCAR1 (0.54) | MAPTALDH1A1LMNAGPR119CYP1A2 | |
| SCHEMBL25424111 | 0.78 | PTGDR2 (0.47) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL31434330 | 0.78 | PTGDR2 (0.47) | PRKCGPRKCBPRKCAPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |