SCHEMBL33526953

SCHEMBL33526953

CC(C)(Cn1nc(F)cc1B1OC(C)(C)C(C)(C)O1)NC(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 3/20 0.40
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
BACE1 P56817 1/20 0.34
BACE2 Q9Y5Z0 1/20 0.34
USP30 Q70CQ3 2/20 0.32
FFAR1 O14842 1/20 0.31
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33526121 0.90 AAK1 (0.43) AAK1PRMT5WDR77BACE1BACE2
SCHEMBL31752616 0.88 AAK1 (0.39) AAK1PRMT5WDR77BACE1BACE2
SCHEMBL1484818 0.73 FFAR1 (0.60) AAK1PRMT5WDR77BACE1BACE2
SCHEMBL33526681 0.71 AAK1 (0.37) AAK1
SCHEMBL16739782 0.71 LPL (0.33) FFAR1
SCHEMBL31752062 0.70 TP53 (0.31)
SCHEMBL33526119 0.67 AAK1 (0.37) AAK1
SCHEMBL33526103 0.67 AR (0.40) AAK1
SCHEMBL33527256 0.67 LMNA (0.48)
SCHEMBL31752066 0.66 TP53 (0.37) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 AAK1 2749/4885PRMT5 2639/4885WDR77 2757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.