SCHEMBL33526962

SCHEMBL33526962

CC(C)(Cn1nccc1Cl)NC(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 10/20 0.38
LATS1 O95835 1/20 0.37
ATR Q13535 1/20 0.37
PCSK9 Q8NBP7 1/20 0.36
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
GAA P10253 2/20 0.34
CYP17A1 P05093 1/20 0.34
STK17B O94768 1/20 0.34
STK17A Q9UEE5 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33526389 0.77 AAK1 (0.38) AAK1LATS1STK17BSTK17A
SCHEMBL33526594 0.74 LATS1 (0.35) AAK1LATS1ATRPOLBMAPK1
SCHEMBL1037007 0.73 PPARA (0.44)
SCHEMBL23138162 0.70 MAPK1 (0.33) MAPK1HPGD
SCHEMBL33526121 0.70 AAK1 (0.43) AAK1
SCHEMBL24803227 0.70 ITGA4 (0.40) AAK1LATS1ATRPCSK9POLB
SCHEMBL33526119 0.70 AAK1 (0.37) AAK1LATS1
SCHEMBL293146 0.69 L3MBTL1 (0.41) LATS1POLBATMLMNA
SCHEMBL34466710 0.69 TP53 (0.35) AAK1LATS1POLBGAALMNA
SCHEMBL33527256 0.68 LMNA (0.48) POLBGAALMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 AAK1 2749/4885LATS1 3736/4885ATR 4261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.