SCHEMBL33527189

SCHEMBL33527189

O=C(O)c1c(F)ccc(Cl)c1CCCO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.38
KDM4E B2RXH2 2/20 0.35
CA2 P00918 1/20 0.35
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 1/20 0.34
ADRA2A P08913 1/20 0.34
CLCN2 P51788 1/20 0.34
TP53 P04637 1/20 0.33
GPR17 Q13304 1/20 0.33
AKR1B1 P15121 1/20 0.33
FABP3 P05413 1/20 0.33
FABP4 P15090 1/20 0.33
PRKAB2 O43741 1/20 0.33
PRKAG1 P54619 1/20 0.33
PRKAA2 P54646 1/20 0.33
PRKAA1 Q13131 1/20 0.33
PRKAG3 Q9UGI9 1/20 0.33
PRKAG2 Q9UGJ0 1/20 0.33
PRKAB1 Q9Y478 1/20 0.33
CNR1 P21554 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24908521 0.78 DPP4 (0.41) DPP4KDM4EALDH1A1HSD17B10ADRA2A
SCHEMBL3414205 0.78 TAAR1 (0.36) KDM4ECA2CNR1L3MBTL1
SCHEMBL33527213 0.74 ALDH1A1 (0.36) KDM4EALDH1A1AKR1B1CNR1
SCHEMBL1467095 0.73 DPP4 (0.50) DPP4KDM4EALDH1A1HSD17B10ADRA2A
SCHEMBL3414495 0.73 TAAR1 (0.35) CA2ALDH1A1CNR1LMNA
SCHEMBL24680171 0.72 DPP4 (0.45) DPP4KDM4EALDH1A1HSD17B10ADRA2A
SCHEMBL27890869 0.71 DPP4 (0.48) DPP4KDM4EALDH1A1HSD17B10ADRA2A
SCHEMBL7820374 0.71 DPP4 (0.48) DPP4KDM4EALDH1A1HSD17B10ADRA2A
SCHEMBL2199784 0.70 TAAR1 (0.63) KDM4ETP53CNR1
SCHEMBL15787544 0.69 P2RX7 (0.40) KDM4ECA2ALDH1A1TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 DPP4 283/4885KDM4E 2674/4885CA2 880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.