SCHEMBL33527198

SCHEMBL33527198

CC(C)(Cc1ccc(F)cc1N)NC(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KCNQ4 P56696 1/20 0.36
KCNQ5 Q9NR82 1/20 0.36
AAK1 Q2M2I8 6/20 0.36
SSTR4 P31391 1/20 0.35
CTSS P25774 2/20 0.35
CTSK P43235 2/20 0.35
GRM2 Q14416 1/20 0.34
HDAC1 Q13547 2/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HDAC2 Q92769 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33525705 0.84 AAK1 (0.41) KCNQ4KCNQ5AAK1CTSSCTSK
SCHEMBL33526231 0.83 CTSS (0.36) KCNQ4KCNQ5AAK1CTSSCTSK
SCHEMBL33526532 0.83 KEAP1 (0.38) KCNQ4KCNQ5AAK1CTSSCTSK
SCHEMBL29726461 0.81 GRM2 (0.44) AAK1CTSSCTSKGRM2HDAC1
SCHEMBL19491486 0.78 NR1H2 (0.40) AAK1
SCHEMBL33526561 0.77 DDB1 (0.38) KCNQ4KCNQ5AAK1SSTR4
SCHEMBL16410342 0.76 MTNR1A (0.47) HDAC1SLC6A2SLC6A4SLC6A3HDAC2
SCHEMBL6676311 0.76 ALDH1A1 (0.42)
SCHEMBL33526461 0.76 TSHR (0.41)
SCHEMBL27641590 0.75 KEAP1 (0.36) HDAC1SLC6A2SLC6A4SLC6A3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 KCNQ4 2094/4885KCNQ5 2349/4885AAK1 2749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.