SCHEMBL33527905

SCHEMBL33527905

C=COCc1ccc(COC(=O)C=C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.43
THRB P10828 3/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 7/20 0.39
TSHR P16473 6/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CA12 O43570 1/20 0.38
AKR1B10 O60218 1/20 0.38
AKR1B1 P15121 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2556244 0.90 HCAR2 (0.50) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL33527388 0.86 HCAR2 (0.46) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL16125662 0.85 HCAR2 (0.46) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL9419668 0.85 TSHR (0.47) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL17791314 0.85 THRB (0.51) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL4578050 0.85 MEN1 (0.55) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL12367978 0.85 HCAR2 (0.46) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL12268165 0.85 HCAR2 (0.46) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL5386239 0.83 HCAR2 (0.44) HCAR2THRBLMNAALDH1A1TSHR
SCHEMBL9555004 0.83 HCAR2 (0.44) HCAR2THRBLMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method SEIKO EPSON CORP (JP) 2026-04-02 US disclosed
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus SEIKO EPSON CORP (JP) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus KAT8, TAS2R8, NLRP3 HCAR2 3153/4885THRB 1617/4885LMNA 4561/4885
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method JAK1, EED, PI4KA HCAR2 2420/4885THRB 2350/4885LMNA 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.