SCHEMBL33527388

SCHEMBL33527388

C=COCc1cccc(COC(=O)C=C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.46
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
AKR1B10 O60218 2/20 0.38
AKR1B1 P15121 2/20 0.38
CA12 O43570 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
TTR P02766 1/20 0.38
TGM2 P21980 1/20 0.37
MAPT P10636 1/20 0.36
ALDH1A1 P00352 4/20 0.36
PTPRC P08575 1/20 0.36
PTPN1 P18031 1/20 0.36
TSHR P16473 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL227301 0.92 HCAR2 (0.51) HCAR2LMNATHRBAKR1B10AKR1B1
SCHEMBL17601870 0.88 CA12 (0.47) HCAR2THRBAKR1B10AKR1B1CA12
SCHEMBL33527905 0.86 HCAR2 (0.43) HCAR2LMNATHRBAKR1B10AKR1B1
SCHEMBL24270436 0.85 HCAR2 (0.47) HCAR2LMNATHRBAKR1B10AKR1B1
SCHEMBL19487306 0.84 ALDH1A1 (0.56) HCAR2LMNATHRBAKR1B10AKR1B1
SCHEMBL19456975 0.84 HCAR2 (0.46) HCAR2LMNATHRBAKR1B10AKR1B1
SCHEMBL21244248 0.84 HCAR2 (0.46) HCAR2LMNATHRBMAPTALDH1A1
SCHEMBL24172399 0.84 HCAR2 (0.49) HCAR2LMNATHRBAKR1B10AKR1B1
SCHEMBL28325729 0.84 ENPP2 (0.46) HCAR2LMNATHRBALDH1A1CYP3A4
SCHEMBL1898363 0.83 HCAR2 (0.48) HCAR2LMNATHRBAKR1B10AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method SEIKO EPSON CORP (JP) 2026-04-02 US disclosed
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus SEIKO EPSON CORP (JP) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus KAT8, TAS2R8, NLRP3 HCAR2 3153/4885LMNA 4561/4885THRB 1617/4885
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method JAK1, EED, PI4KA HCAR2 2420/4885LMNA 4486/4885THRB 2350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.