SCHEMBL3353076

SCHEMBL3353076

C[Si](C)(C)Oc1ccc(O[Si](C)(C)C)c(-c2ccccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
MAPK1 P28482 1/20 0.43
RECQL P46063 1/20 0.43
KDM4E B2RXH2 4/20 0.41
SYK P43405 1/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
PIN1 Q13526 1/20 0.37
BACE1 P56817 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
ACACA Q13085 1/20 0.36
LMNA P02545 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4206525 0.79 ADRA2A (0.47) L3MBTL1MAPK1KDM4ENPC1RAB9A
SCHEMBL29031571 0.74 NPC1 (0.47) L3MBTL1MAPK1KDM4ENPC1RAB9A
SCHEMBL835688 0.72 KDM4E (0.64) L3MBTL1MAPK1RECQLKDM4ESYK
SCHEMBL29572032 0.72 KDM4E (0.64) L3MBTL1MAPK1RECQLKDM4ESYK
SCHEMBL8463554 0.71 MAPT (0.32) L3MBTL1KDM4EMAPT
Iodide SCHEMBL30084369 0.70 KDM4E (0.62) L3MBTL1MAPK1RECQLKDM4ESYK
SCHEMBL18925853 0.69 ALDH1A1 (0.39) L3MBTL1MAPK1KDM4ENPC1RAB9A
SCHEMBL10678435 0.69 SMN1; SMN2 (0.38) L3MBTL1MAPK1KDM4ENPC1RAB9A
SCHEMBL8501330 0.69 L3MBTL1 (0.60) L3MBTL1MAPK1RECQLKDM4ESYK
SCHEMBL232678 0.69 CA4 (0.48) KDM4ENPC1RAB9ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2046491-B1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF, AND USE LEIBNIZ INST POLYMERFORSCHUNG (DE) 2010-05-12 EP disclosed
EP-2046491-A2 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF, AND USE Leibniz-Institut für Polymerforschung Dresden e.V. (DE) 2009-04-15 EP disclosed
WO-2008012222-A2 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF, AND USE LEIBNIZ-INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E.V. (DE) 2008-01-31 WO disclosed
EP-0909301-A1 BIODEGRADABLE LIQUID CRYSTALLINE POLYMERS Smith & Nephew plc (GB) 1999-04-21 EP disclosed
WO-1997048782-A1 BIODEGRADABLE LIQUID CRYSTALLINE POLYMERS SMITH & NEPHEW PLC (GB) 1997-12-24 WO disclosed