Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353142 | 0.93 | MC4R (0.62) | MC4RALDH1A1TAAR1GLA | |
| SCHEMBL3346679 | 0.84 | MC4R (0.59) | MC4RKMT2AALDH1A1TAAR1MEN1 | |
| SCHEMBL3346376 | 0.82 | MC4R (0.63) | MC4RALDH1A1TAAR1GLASMN1; SMN2 | |
| SCHEMBL3353136 | 0.81 | TAAR1 (0.50) | MC4RKMT2AALDH1A1TAAR1GLA | |
| SCHEMBL3346234 | 0.80 | MC4R (0.71) | MC4RKMT2AALDH1A1TAAR1 | |
| SCHEMBL3347960 | 0.79 | CNR1 (0.52) | MC4RKMT2AALDH1A1TAAR1MEN1 | |
| SCHEMBL3349847 | 0.76 | MC4R (0.58) | MC4RKMT2AALDH1A1TAAR1MEN1 | |
| SCHEMBL3348167 | 0.76 | MC4R (0.60) | MC4RKMT2AALDH1A1TAAR1 | |
| SCHEMBL3410126 | 0.76 | MC4R (0.57) | MC4RTAAR1SMN1; SMN2 | |
| SCHEMBL3346447 | 0.75 | MC4R (0.63) | MC4RALDH1A1TAAR1GLALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |