Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354323 | 0.84 | LMNA (0.43) | ALDH1A1LMNAMAPTTDP1HTT | |
| SCHEMBL3353890 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL3359038 | 0.80 | LMNA (0.47) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL6975821 | 0.79 | MAPT (0.52) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL6819520 | 0.78 | LMNA (0.49) | ALDH1A1LMNAMAPTTDP1NPC1 | |
| SCHEMBL7288753 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL5802973 | 0.78 | MAPT (0.52) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL11661312 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL383187 | 0.74 | L3MBTL1 (0.44) | ALDH1A1LMNAMAPTKDM4ETDP1 | |
| SCHEMBL3173753 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | KHAMRAI UTTAM | 2010-06-17 | — | — | US | disclosed |
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | CCR1, CCR4, CCR5 | ALDH1A1 903/4885LMNA 3702/4885MAPT 4510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.