Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359038 | 0.95 | LMNA (0.47) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL6975821 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL5802973 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL3353885 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNATDP1HTT | |
| SCHEMBL17432580 | 0.77 | L3MBTL1 (0.60) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL6210271 | 0.77 | LMNA (0.48) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL3359039 | 0.76 | XDH (0.43) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL7677025 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL7673654 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL624054 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7076581-A | — | — | None | — | — | JP | disclosed |
| JP-H0776581-A | INDUSTRIAL PRODUCTION OF 1,4-BENZOXAZINE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1995-03-20 | — | — | JP | disclosed |
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |