Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354799 | 0.86 | TRPV1 (0.65) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL3358957 | 0.86 | TRPV1 (0.65) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL3356075 | 0.83 | MEN1 (0.43) | TRPV1 | |
| SCHEMBL3356086 | 0.81 | L3MBTL1 (0.41) | TRPV1 | |
| SCHEMBL2319982 | 0.76 | TRPV1 (0.68) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL2320518 | 0.75 | TRPV1 (1.00) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL2319990 | 0.75 | TRPV1 (1.00) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL13459509 | 0.75 | ALDH1A1 (0.36) | TRPV1 | |
| SCHEMBL13459130 | 0.72 | POLB (0.44) | — | |
| SCHEMBL616146 | 0.72 | TRPV1 (0.76) | TRPV1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023512-A1 | NOVEL VANILLOID RECEPTOR MODULATORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LABORATORIES LTD. (IN) | 2010-03-04 | — | — | WO | claimed |
| WO-2010023512-A1 | NOVEL VANILLOID RECEPTOR MODULATORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LABORATORIES LTD. (IN) | 2010-03-04 | — | — | WO | disclosed |