Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13459159 | 0.89 | L3MBTL1 (0.39) | L3MBTL1TSHRNPSR1NPC1POLB | |
| SCHEMBL3356075 | 0.81 | MEN1 (0.43) | TRPV1POLBHTTKMT2AMEN1 | |
| SCHEMBL3354668 | 0.81 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL13459509 | 0.80 | ALDH1A1 (0.36) | L3MBTL1TSHRNPSR1NPC1TRPV1 | |
| SCHEMBL13459130 | 0.79 | POLB (0.44) | L3MBTL1TSHRNPSR1POLBKMT2A | |
| SCHEMBL3386118 | 0.77 | ALDH1A1 (0.40) | L3MBTL1TSHRNPSR1POLBKMT2A | |
| SCHEMBL3355152 | 0.73 | ALDH1A1 (0.43) | L3MBTL1TSHRNPSR1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL25390853 | 0.72 | ALDH1A1 (0.42) | L3MBTL1TSHRNPSR1POLBKMT2A | |
| SCHEMBL21624825 | 0.70 | POLB (0.47) | L3MBTL1TSHRNPC1POLBTDP1 | |
| SCHEMBL23387224 | 0.70 | POLB (0.47) | L3MBTL1TSHRNPC1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023512-A1 | NOVEL VANILLOID RECEPTOR MODULATORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LABORATORIES LTD. (IN) | 2010-03-04 | — | — | WO | claimed |
| WO-2010023512-A1 | NOVEL VANILLOID RECEPTOR MODULATORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LABORATORIES LTD. (IN) | 2010-03-04 | — | — | WO | disclosed |