SCHEMBL3354992

SCHEMBL3354992

CCNCCC[Si](OC)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 11/20 0.40
DRD4 P21917 11/20 0.40
DRD3 P35462 9/20 0.40
HTT P42858 1/20 0.40
RECQL P46063 1/20 0.35
ADRB2 P07550 1/20 0.35
HTR1B P28222 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3350037 0.97 DRD2 (0.40) DRD2DRD4DRD3HTTRECQL
SCHEMBL3353015 0.92 HTT (0.42) DRD2DRD4DRD3HTTRECQL
SCHEMBL3383380 0.89 DRD2 (0.42) DRD2DRD4DRD3HTTCYP1A2
SCHEMBL3386839 0.86 DRD2 (0.42) DRD2DRD4DRD3HTTCYP1A2
SCHEMBL1608986 0.82 LTA4H (0.43) DRD2DRD3HTTRECQLADRB2
Aniline SCHEMBL6816049 0.81 HTT (0.40) DRD2DRD4DRD3HTTRECQL
SCHEMBL3385240 0.81 SIGMAR1 (0.45) DRD2DRD4DRD3HTT
Benzylamine SCHEMBL5686028 0.79 LOXL2 (0.41) DRD2DRD4DRD3HTTCYP1A2
SCHEMBL19816665 0.78 LTA4H (0.43) DRD2DRD3HTTRECQLADRB2
SCHEMBL1609512 0.78 CA4 (0.39) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100010166-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2010-01-14 US disclosed
EP-2064256-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2009-06-03 EP disclosed
WO-2008031895-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2008-03-20 WO disclosed