Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.47 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355596 | 0.99 | ALDH1A1 (0.55) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL3351522 | 0.90 | HTR6 (0.51) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL2075237 | 0.89 | HRH3 (0.53) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL3356257 | 0.89 | CACNB4 (0.58) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL3352554 | 0.88 | KMT2A (0.51) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL3352978 | 0.88 | CACNB4 (0.56) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL9400557 | 0.80 | MAPT (0.51) | MEN1LMNAKMT2ACDK2CNR1 | |
| SCHEMBL3357630 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL3353450 | 0.79 | HTR6 (0.62) | ALDH1A1LMNAPKMCDK2CACNB4 | |
| SCHEMBL3355292 | 0.79 | HTR6 (0.59) | MEN1LMNAKMT2ACDK2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |