Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 6/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355596 | 0.91 | ALDH1A1 (0.55) | HTR6KCNJ1KCNH2CDK2HTR7 | |
| SCHEMBL3355597 | 0.90 | ALDH1A1 (0.57) | HTR6KCNJ1KCNH2CDK2HTR7 | |
| SCHEMBL3353450 | 0.89 | HTR6 (0.62) | HTR6CDK2HTR7ALDH1A1LMNA | |
| SCHEMBL3352554 | 0.88 | KMT2A (0.51) | HTR6KCNJ1CDK2ALDH1A1MEN1 | |
| SCHEMBL2075237 | 0.81 | HRH3 (0.53) | KCNJ1KCNH2CDK2HTR7ALDH1A1 | |
| SCHEMBL9400557 | 0.80 | MAPT (0.51) | CDK2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3352978 | 0.80 | CACNB4 (0.56) | HTR6CDK2ALDH1A1MEN1KMT2A | |
| SCHEMBL3356257 | 0.79 | CACNB4 (0.58) | HTR6CDK2ALDH1A1MEN1KMT2A | |
| SCHEMBL3356418 | 0.79 | HTR6 (0.54) | HTR6CDK2HTR7LMNASMN1; SMN2 | |
| SCHEMBL3355292 | 0.79 | HTR6 (0.59) | HTR6CDK2HTR7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |